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Error message

Warning: Cannot modify header information - headers already sent by (output started at /home/grandsvire/2017/index.php:2) in drupal_send_headers() (line 1501 of /home/grandsvire/2017/includes/bootstrap.inc).
PDOException: SQLSTATE[HY000] [2003] Can't connect to MySQL server on 'grandsviregvvm.mysql.db' (111) in lock_may_be_available() (line 167 of /home/grandsvire/2017/includes/lock.inc).